align-items

                                
<div id="wrap">
    <div class="flexArea ai-center">
        <div class="flexItem">
            <span>Item</span>
        </div>
        <div class="flexItem">
            <span>Item</span>
        </div>
    </div>

    <div class="flexArea ai-start">
        <div class="flexItem">
            <span>Item</span>
        </div>
        <div class="flexItem">
            <span>Item</span>
        </div>
    </div>

    <div class="flexArea ai-end">
        <div class="flexItem">
            <span>Item</span>
        </div>
        <div class="flexItem">
            <span>Item</span>
        </div>
    </div>
</div>

                                        
#wrap{padding: 50px; box-sizing: border-box;
    .flexArea{display: flex;
        .flexItem{display: flex; width: 200px; height: 200px; max-width: 200px; font-size: 16px; font-family: 'Noto Sans'; 
        color: #fff; background-color: #000;
            +.flexItem{margin-left: 10px;}
        }
        &.ai-center .flexItem{align-items: center;}
        &.ai-start .flexItem{align-items: flex-start;}
        &.ai-end .flexItem{align-items: flex-end;}
    }
}

                                        
#wrap{
    padding: 50px;
    -webkit-box-sizing: border-box;
    box-sizing: border-box;
}

#wrap .flexArea {
    display: -webkit-box;
    display: -ms-flexbox;
    display: flex;
}

#wrap .flexArea .flexItem {
    display: -webkit-box;
    display: -ms-flexbox;
    display: flex;
    width: 200px;
    height: 200px;
    max-width: 200px;
    font-size: 16px;
    font-family: 'Noto Sans';
    color: #fff;
    background-color: #000;
}

#wrap .flexArea .flexItem + .flexItem {
    margin-left: 10px;
}

#wrap .flexArea.ai-center .flexItem {
    -webkit-box-align: center;
        -ms-flex-align: center;
            align-items: center;
}

#wrap .flexArea.ai-start .flexItem {
    -webkit-box-align: start;
        -ms-flex-align: start;
            align-items: flex-start;
}

#wrap .flexArea.ai-end .flexItem {
    -webkit-box-align: end;
        -ms-flex-align: end;
            align-items: flex-end;
}

Esc 혹은 우측 상단 X 버튼을 눌러 결과창을 닫을 수 있습니다.

display : align-items

Item